Call for Joint Action “Nutrition & the Epigenome”

The second non-cofunded action in ERA-HDHL

JPI HDHL is pleased to launch a new call to create dedicated, top-class transnational research consortia in the emerging field of nutrition and epigenetics. Previous research has studied epigenetic changes in early life. However, the effects of diet on epigenetic regulation, gene expression in different tissues, and subsequent metabolic health and disease are still unclear. Experts need to better understand the mechanistic pathways that link dietary interventions to those epigenetic changes that have functional/physiological consequences to the tissue and ultimately the organism.

Aim of the call

The aim of this call is to support transnational, collaborative research projects that gain a better understanding of the diet-epigenome relationships and their effect on human health. This will allow the development and substantiation of intervention strategies for treating nutrition-related diseases and sustaining good health throughout the life course.

Call topics

Proposals should focus on diet and epigenome, and cover one of the following areas:

  • Establishing cause-and-effect relationships between diet, the epigenome and metabolic health
  • Identifying risk factors and early stage epigenetic changes
  • Epigenetic effects across the lifespan and inter (and potentially trans) generational epigenetic effects
  • Investigation of modifiable factors that could be involved in epigenetic regulation
  • The effect of diet and nutritional status on the intra-uterine environment

Funding and submission

In total, 10 countries participate in this call with a total budget of more than 8M euro. In general, joint research proposals may be submitted by applicants working in universities (or other higher education institutions), non-university public research institutes, hospitals and other health care settings. Participation of private parties is encouraged as well as commercial companies, in particular small and medium-size enterprises. However, the eligibility of these organisations and institutions are subject to the national/regional regulations of the individual funding organisations and may therefore vary.

The proposals must be submitted by the coordinator in electronic format no later than 12th April 16.00 CEST, 2018 via the Electronic Submission System of JPI HDHL.

Call time schedule



6th February 2018

Publication of the Call

12th April 2018

Submission deadline proposals

1st June 2018

Send reviewers comment to applicants

11th June 2018

Deadline submission rebuttal letter

2nd - 3rd July 2018

SEC & CSC meeting to discuss proposal

20th September 2018

Final funding decision

For further information, please check the call documents:

Proposals should be submitted through the Electronic Submission System. No other means of submission will be accepted.
Researchers who want to participate in a consortium need to register in the Meta Data Base of the JPI HDHL website.


For questions about the call:

Name: Dr. Wilke van Ansem (Programme Officer)
Telephone: +31 (0) 70 3495164

For technical questions regarding the Electronic Submission System:
Name: Andrea Romano

Source: Please, find further information on